Frequently Asked Questions

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Frequently Asked Questions

FAQ

  • How do I select the type of viral vector needed for my research?

    AAV has been developed for the construction of viral vector candidates mainly for the purpose of gene therapy due to a number of attractive advantages. Advantages and drawbacks of AAV vector-mediated gene transfer are summarized below. Advantages: i) Great biosafety; the wild type AAVs are not known to cause disease in vivo, and most AAV genome elements have been removed for further security of gene delivery in vivo. ii) Low immunogenicity; AAV causes a mild immune response in vivo, providing support to their pathogenicity during gene delivery. iii) Broad range of infectivity. AAV can infect both dividing and quiescent cells in vivo, allowing gene delivery to a highly diverse range of cell types. 4) Stable expression. Long term gene delivery in vivo can be mediated by AAV. No integration into the genome.

  • How do I obtain a quotation and place an order for a pre-made or customized vector?

    Please contact us directly by email as indicated in our Home Page and we will provide a detailed response and personalized assistance to your research needs and inquiries.

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