The development of a robust and high yield cell culture process is a critical stage for the effective manufacturing of biological product.
At VVector Bio high-throughput screening can be perform at various scale ranging from 20 mL spin tubes; 20-50 mL shake flask to fully controlled 250 mL mini-bioreactor (Ambr250).
In order to limit cost and time of the project, Design of Experiments (DOE) is used as a tool to identify the critical process parameter.
Cell culture process validation can be operated at 1L to 3L bioreactor scale.
Intensification strategies includes:
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